Choline is thought to play a role in preventing heart disease. It works with other Vitamin B's, especially folic acid, to metabolize homocysteine; a by-product of protein metabolism that increases the risk of atherosclerosis when too much circulates in the blood. Choline may also protect the liver against accumulation of excessive fat, cirrhosis, and cancer. Choline, along with the closely related lecithin, is important in reproduction and fetal development. The body can make Choline, but sometimes not enough to meet its needs, especially during pregnancy and breast feeding as well as exerting exercising with high intensity. Choline also protects against fatty liver disease and other liver disorders. Choline can also help prevent atherosclerosis and heart disease.