Supports Healthy Heart Muscle*
with Lecithin & Vitamin E
Coenzyme Q10 is a vitamin-like compound also called ubiquinone. It is an essential component of cells and is necessary for mitochondrial energy production. Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*
CoEnzyme Q-10 (CoQ-10) is a natural compound that is being used clinically to medically treat heart disease in Japan , Italy and China . CoQ-10 is also used as a natural health product in the USA , Canada and some other countries.
In the human body, CoQ-10 is found concentrated in the heart and liver tissue, where it functions in the respiratory electron transport system in mitochondria. Consequently, its toxicity to the human body is extremely low. It has ten isoprene units forming a side chain attached to benzoquinone ring and all the ten double bonds in the side chain should be ''trans'' form to be physiologically effective in medicinal applications.
Two manufacturing processes are currently being used in Japan to commercially produce CoQ-10:
1. Chemical synthesis process
2. Microbial fermentation process
In the case of chemical synthesis, relatively higher rates of ''cis''-isomers in the side chain (pharmacologically less active form) and Coenzyme Q-9 which has only 9 isoprene units in the side chain are formed as byproducts which must be eliminated from the final product through a purification process. On the other hand, the natural fermentation process yields the ''all-trans'' form Q-10 (pharmacologically active form), resulting in scarcely a trace of Coenzyme Q-9
We have expanded our efforts in the research and development of Single Cell Proteins (microbial protein). They have established a unique continuous fermentation process utilizing these single microbial cells, which does not allow contamination by undesirable organisms.
Based on this technology, they have developed their own proprietary process for the production of CoQ-10. The process uses a selected kind of Non-Genetically Modified Microorganism that is cultivated in a continuous fermentor. The fermentation broth is extracted, and then further purified by a column chromatographic process to yield pure CoQ-10. The whole process is controlled under GMP (Good Manufacturing Practice) and the product is closely monitored according to the ''Standards for Ingredients of Drugs.
In addition to purchasing what we believe is the purest CoEnzymeQ-10 powder manufactured, we analyze the incoming bulk material and each of our finished products. Our laboratory staff utilizes a sophisticated HPLC method to assure proper potency of CoQ-10.
What is CoQ10 and what is it good for?
CoQ10 (Co-enzyme Q10) is a vitamin-like compound also known as ubiquinone. Ubiquinone combines two terms to describe this substance -quinone is a type of coenzyme and ubiquitous indicates it exists everywhere in the human body. CoQ10 plays an important role in the body's energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP (Adenosine triphosphate), a key energy storage molecule. Without CoQ10, you would not be alive.
CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body's production of CoQ10 declines by as much as 80%. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body.
The highest levels of CoQ10 are found in tissues in the body that work the hardest; like the heart, the liver, etc. Initial studies into CoQ10 found that persons with cardiac insufficiencies had very low levels of CoQ10, and that supplementation increased CoQ10 levels. So CoQ10 is not only an effective antioxidant, but it supports cardiovascular health as well.
How and when should I take CoQ10?
CoQ10 works better if taken with fats and oils. Many CoQ10 supplements contain oils in the base and are sold as liquid filled softgel capsules. All forms of CoQ10 will work better if taken with a meal containing fats or with healthy supplements providing fat, such as fish oil, flax oil, coconut oil, etc.
What about the quality of NOW's CoQ10?
LifeSource sells only the natural, 100% all-trans form of CoQ10 that is produced using natural fermentation and purchased from the leading Japanese suppliers. This is considered to be the best and most natural form available. Differences in absorption or utilization of CoQ10 products are mostly associated with oils added to powdered CoQ10 within a softgel capsule. These differences are far less important when the supplement is taken at the same time as other oils or oil-based supplements in the diet, rather than between meals. This makes it possible to take CoQ10 in a vegetarian form - or even as a powder - and still enjoy the benefits of enhanced absorption.